Family Guy Season 22 Characters & Cast — No Spoilers
Every character in Family Guy season 22 with photos and the actors who play them, including Seth MacFarlane, Alex Borstein, Mila Kunis — spoiler-free, nothing from later seasons.
- Peter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire (voice) — played by Seth MacFarlane
- Lois Griffin / Tricia Takanawa / Loretta Brown / Barbara Pewterschmidt (voice) — played by Alex Borstein
- Meg Griffin (voice) — played by Mila Kunis
- Chris Griffin (voice) — played by Seth Green
- Joe Swanson (voice) — played by Patrick Warburton
- Cleveland Brown (voice) — played by Arif Zahir
- Siri (voice) / Sarah Koenig (voice) / Rioter (voice) / Jamie Lee Curtis (voice) / Jane Fonda (voice) / Woman in Movie / Reporter (voice) / Time Machine (voice) / Secretary (voice) — played by Rachael MacFarlane
- (voice) / Elliott (voice) / Announcer (voice) / Josh Universal (voice) — played by John Viener
- (voice) / Brad Pitt (voice) / Corey (voice) — played by Damien Fahey
- 1980s Producer (voice) / Meg's Boss (voice) / (voice) — played by Ralph Garman
- (voice) / John Davidson (voice) / Tommy Lee Jones (voice) / Kevin James (voice) — played by Josh Robert Thompson
- Bonnie Swanson (voice) — played by Jennifer Tilly
- Cocky Jogger (voice) / (voice) / Manatee (voice) / Leeds Employee (voice) — played by Travis Bowe
- Tour Guide (voice) / Diner #3 / Wedding Guest #3 (voice) / Cruise Ship Passenger #3 (voice) / Student #3 (voice) — played by Steve Callaghan
- James (voice) / (voice) / Kanye West (voice) / Coffee Shop Patron (voice) — played by Jay Pharoah
- Donna Tubbs (voice) — played by Sanaa Lathan
- Principal Shepherd (voice) — played by Gary Cole
- Wild Wild West (voice) — played by Sam Elliott
- Montage Singer (voice) / Sex Jingle Singer (voice) — played by Patrick Stump
- Emma (voice) / (voice) — played by Mae Whitman
All seasons of Family Guy: full spoiler-free character guide