American Dad! Season 21 Characters & Cast — No Spoilers
Every character in American Dad! season 21 with photos and the actors who play them, including Seth MacFarlane, Wendy Schaal, Rachael MacFarlane — spoiler-free, nothing from later seasons.
- Stan Smith / Roger (voice) — played by Seth MacFarlane
- Francine Smith (voice) — played by Wendy Schaal
- Hayley Smith (voice) — played by Rachael MacFarlane
- Steve Smith (voice) — played by Scott Grimes
- Klaus (voice) — played by Dee Bradley Baker
- Jeff Fischer (voice) — played by Jeff Fischer
- Billy (voice) / Principal Lewis (voice) — played by Kevin Michael Richardson
- Al Tuttle (voice) — played by Richard Kind
- Memphis Stormfront (voice) — played by Andy Daly
- Dick (voice) / Randy Goodtimes (voice) / Wilbur Kentucky (voice) — played by David Koechner
- Buckle (voice) / Santa Claus (voice) / Caller (voice) — played by Matt McKenna
- Avery Bullock (voice) — played by Patrick Stewart
- Snot Lonstein (voice) — played by Curtis Armstrong
- Parker (voice) / Bouncer (voice) — played by Parker Deay
- Captain (voice) / Dr. Kalgary (voice) / Dominic (voice) — played by Alan Tudyk
- Dr. Weitzman (voice) — played by Matt E. Mixer
- Doctor (voice) / James Garfield (voice) / Funeral Speaker (voice) — played by Chris Parnell
- Jackson (voice) — played by Mike Henry
- (voice) / Cameraman (voice) / Mailman (voice) — played by Nic Wegener
- Trish (voice) — played by Casey Wilson
All seasons of American Dad!: full spoiler-free character guide